Schistosomiasis-pulmonary hypertension review published

A review written by Brian Graham on schistosomiasis associated pulmonary arterial hypertension was published in Advances in Pulmonary Hypertension. https://meridian.allenpress.com/aph/article/21/4/109/489433/Schistosomiasis-Associated-Pulmonary-Arterial

Review paper on exercise metabolomics published

Dr. Michael Lee is the first author on a review paper published in Frontiers in Physiology, which covers exercise physiology in pulmonary hypertension and its relationship to metabolism of the pulmonary vasculature. The senior author is close collaborator Dr. Rudolf Oliveira at the Federal...

Paper describing RV macrophage role published

Collaborator Dr. Sue Gu at UCDenver was the first author of a publication in Pulmonary Circulation on the role of right ventricle macrophages in pulmonary hypertension. We found an increase in a population of interstitital RV macrophages, and clodronate treatment to deplete monocytes/macrophages...

Paper describing fatty acid oxidation in pulmonary hypertension published

Congratulations Dr. Michael Lee for publishing in AJP-Lung on the role of fatty acid oxidation in pulmonary hypertension, using a combination of human tissue analysis and animal model work.  https://pubmed.ncbi.nlm.nih.gov/35763400/

Paper describing the use of dexamethasone as prophylaxis for high altitude disease published

This clinical study led by Prof. Pasha (IGIB, India) found that dexamethasone prophylaxis prior to travelling to high elevation benefits women more than men, including preventing the acute rise in right ventricle systolic pressure. Drs. Rahul Kumar and Brian Graham were co-authors on this paper,...

Biruk Kassa going to UCSF pharmacy school

Mr. Biruk Kassa, who joined our lab 6 years ago, is leaving our lab to attend UCSF Pharmacy School. Biruk started as an undergraduate worked when he was at UCDenver, and then received a post-baccalauraute diversity supplement to work in our lab. Biruk moved with us to UCSF 3 years ago. During his...

Michael Lee awarded Fulbright Scholarship

Congratulations Mike for receipt of a Fulbright Scholarship! Mike will be travelling to the Federal University of São Paulo (UNIFESP), Brazil for 4 months to learn exercise right heart catheterization and metabolomics with our collaborator Dr. Rudolf Oliveria.

Paper describing our collaboration investigating schistosomiasis-PAH in Ethiopia and Zambia published

This paper published in Pulmonary Circulation describes our plan to screen patients with Schistosoma hepatosplenic disease for pulmonary hypertension using echocardiography. The co-first authors are Dr. Edford Sinkla (Lusaka, Zambia) and Dr. Hanan Ahmed (Addis Ababa, Ethiopia).  https://pubmed....

S. japonicum paper published

Biruk Kassa is the first author of a paper describing the phenotype of experimental PH caused by Schistosoma japonicum was published in PLOS-NTD. We found that mice exposed to S. japonicum develop PH, which is more mild than after S. mansoni, and the antigens between the 2 parasites are...

Welcome Dara Fonseca Balladares

Ms. Fonseca Balladares joins our lab as a junior specialist after graduating from UC Merced. We met Dara through the UCSF matchmaking event for post-baccalaurates looking for research projects, who are under-represented in medicine and thinking about applying to medical school in the future. Dara's...